Shaun struggles with his role as Lea’s partner after complications arise with the pregnancy and his instincts as a medical professional kick in. Meanwhile, Dr. Park, Dr. Andrews and Asher disagree on how to address an elderly patient’s wishes.
After a political protest turns violent, the team races to save two young gunshot victims.
After finding out the gender of their unborn child, Lea’s enthusiasm prompts Shaun to make an effort to be a more supportive partner. Meanwhile, the team treats a navy pilot whose previous doctor’s misdiagnosis compromises her chances at a full recovery.
Claire is blindsided when her absentee father shows up at her door. Meanwhile Shaun feels disconnected with Lea, causes tension in their relationship.
When a renowned surgeon comes to St. Bonaventure for treatment, the team’s enthusiasm is quickly overshadowed by the doctor’s behavior. After studying his case, Dr. Shaun Murphy sees a pattern he recognizes. Meanwhile, Shaun and Lea are forced to make a life-changing decision that will alter the course of their relationship.
After bringing in an incredibly unique and complicated spinal surgery, Dr. Aaron Glassman challenges the residents for an opportunity to join him in the operating room. Meanwhile, Shaun and Morgan disagree on how to treat a comatose patient with a cancerous tumor.
When the hospital is hit with a cyber attack threatening to shut down life-saving machines, Lea rises to the challenge and looks to outsmart the hackers to prove herself.
Claire, Enrique and Andrews treat Zara, an African-American medical marjuana dispensary owner; after racially profiling Zara upon admission to the hospital, Claire’s mistake nearly kills her.
The team treats a teenage gymnast who experiences complications from her intensive training. Shaun meets Lea’s parents for the first time.
Dr. Morgan Reznick discovers her patient’s wealth and obsession with extending his life is a dangerous mix that could end up costing more than he can afford.
Chief of Surgery Dr. Audrey Lim struggles to cope with the residual emotional trauma of COVID-19.
Shaun questions his decision to give the new residents autonomy when one of his intern’s misdiagnosis of a patient has dire consequences. Morgan and Park bond over failed relationships.