Shaun confronts Salen about the many changes she has implemented since coming on at St. Bonaventure, and Glassman is forced to accept his new role at the hospital.
Dr. Shaun Murphy and the team race to save a pregnant woman’s baby and find her current situation as a convicted felon complicates it even more than they realize. Meanwhile, the hospital takes on some unexpected changes that the staff are not prepared for.
Shaun and Lea’s upcoming engagement party has everyone in a festive mood after their return from Guatemala. Meanwhile, a young single mother learns her son may have contracted his cancer from a surprising source, and Mateo finds out if his previous issues in America will be resolved.
Dr. Shaun Murphy must perform a risky surgery on a patient without electricity when the power suddenly goes out at the hospital in Guatemala. Additionally, Dr. Lim and Dr. Mateo Rendón Osma’s relationship deepens as they overcome difficulties during their surgery.
During part one of the two-part season finale, the St. Bonaventure team travels to Guatemala on a surgical mission to help patients at a rural hospital. Once there, the team faces a small community that is in desperate need of their help but are assigned the daunting task of identifying who they can help most. And while Shaun seems to be thriving in Guatemala, Lea is still struggling with the loss of her baby.
Shaun and Lea go on a camping trip to distract themselves from their grief over their miscarriage. Meanwhile, Morgan and Park argue about the best course of treatment for their patient.
Dr. Claire Brown and the team must face hard truths about what lines they are willing to cross when one of Claire’s idols becomes her patient.
Shaun struggles with his role as Lea’s partner after complications arise with the pregnancy and his instincts as a medical professional kick in. Meanwhile, Dr. Park, Dr. Andrews and Asher disagree on how to address an elderly patient’s wishes.
After a political protest turns violent, the team races to save two young gunshot victims.
After finding out the gender of their unborn child, Lea’s enthusiasm prompts Shaun to make an effort to be a more supportive partner. Meanwhile, the team treats a navy pilot whose previous doctor’s misdiagnosis compromises her chances at a full recovery.
Claire is blindsided when her absentee father shows up at her door. Meanwhile Shaun feels disconnected with Lea, causes tension in their relationship.
When a renowned surgeon comes to St. Bonaventure for treatment, the team’s enthusiasm is quickly overshadowed by the doctor’s behavior. After studying his case, Dr. Shaun Murphy sees a pattern he recognizes. Meanwhile, Shaun and Lea are forced to make a life-changing decision that will alter the course of their relationship.
After bringing in an incredibly unique and complicated spinal surgery, Dr. Aaron Glassman challenges the residents for an opportunity to join him in the operating room. Meanwhile, Shaun and Morgan disagree on how to treat a comatose patient with a cancerous tumor.
When the hospital is hit with a cyber attack threatening to shut down life-saving machines, Lea rises to the challenge and looks to outsmart the hackers to prove herself.
Claire, Enrique and Andrews treat Zara, an African-American medical marjuana dispensary owner; after racially profiling Zara upon admission to the hospital, Claire’s mistake nearly kills her.
The team treats a teenage gymnast who experiences complications from her intensive training. Shaun meets Lea’s parents for the first time.
Dr. Morgan Reznick discovers her patient’s wealth and obsession with extending his life is a dangerous mix that could end up costing more than he can afford.
Chief of Surgery Dr. Audrey Lim struggles to cope with the residual emotional trauma of COVID-19.
Shaun questions his decision to give the new residents autonomy when one of his intern’s misdiagnosis of a patient has dire consequences. Morgan and Park bond over failed relationships.